Emily joined the Hata Lab in June 2022 after receiving her BA from College of the Holy Cross. At Holy Cross, Emily was a Biology/Chinese double major, and worked in Dr. Alexis Hill’s Drosophila Neurobiology lab. Her work focused on the gene seizure (sei) and how it affects developmental time in Drosophila, along with determining which cell types express sei. In the Hata lab, she is a member of the Model Development Team which seeks to create cell lines and PDX models from patient lung cancer samples. Outside of lab, Emily enjoys doing ballet, playing with her cat, and spending time with friends and family.
Toshio joined the Hata Lab in April 2022. He received his MD at Nagoya City University, Japan and practiced as a thoracic surgeon in Japan, where he developed a great interest in cancer biology. He then obtained his Ph.D. at Kindai University, Japan, where he studied the resistance mechanism to MET-TKIs in lung cancer harboring MET exon 14 skipping mutation in the laboratory of Dr. Tetsuya Mitsudomi.Toshio is currently focusing on drug persister cancer cell and acquired resistance to targeted therapies especially in ALK-positive lung cancer.Despite of the initial drastic efficacy of molecular targeted therapy, all patients inevitably develop resistance. Toshio believes that his project will contribute to establish new treatment strategies for lung cancer to prevent the drug resistance.
Radhika joined the Hata lab in 2022. She did her Masters in Virology from the National Institute of Virology, India. Radhika received PhD in Cell and Molecular biology from the University of Toledo, Ohio. During her graduate school in Dr. William R. Taylor lab her research focused on the spindle assembly checkpoint and mitotic spindle architecture. In the Hata lab she is working on understanding the role of tumor micro-environment in EGFR mutant lung cancers. Along with mutations in tumor cells, components from tumor micro-environment impact patient response to tyrosine kinase inhibitors. Her goal is to dissect such pathways used by tumor cells for communicating with the surround cells and provide strategies to overcome acquired resistance in lung cancer. In her free time Radhika enjoys hiking, badminton and reading
Katie joined the Hata lab in December 2021 after earning her BS/MS in Biology from Tufts University. At Tufts, she conducted undergraduate research with Julia Gouvea, studying the learning and teaching practices of Biology at multiple grade levels. Dr. Gouvea’s research investigates how model-based reasoning as a biological practice can support deeper learning for students. In the Hata lab, Katie works with Samar on identifying therapeutic strategies for KRAS NSCLS. Outside of the lab, she enjoys riding her bike and teaching others how to ride at the Bicycle Riding School!
Chendi received her Bachelor of Science degree in Biological Science as an honors graduate from Shaanxi Normal University, China. She then completed a PhD in the Department of Biochemistry at Boston University School of Medicine (BUSM) where her research in the laboratory of Dr. Stephen Farmer focused on understanding the mechanisms of energy expenditure and stem cell fate in brown adipose tissue. Chendi joined the Hata laboratory as a research fellow in June 2017 in order to pursue a new direction in translational cancer research. One of Chendi’s research interests is to identify novel targeted therapeutic strategies for KRAS mutant NSCLC, a subset of lung cancers that have so remained refractory to targeted approaches. She is particularly interested in targeting vulnerability of subsets of KRAS mutant NSCLC bearing different co-occurring mutations. In addition, Chendi is interested in deciphering the evolution of lung cancer heterogeneity by utilizing computational and “omic” approaches. Outside work, Chendi is training as a Chinese martial artist, is a professional Erhu player and a certified scuba diver. Chendi also has a passion for different types of music, especially classic rock!
Lia joined the Hata Lab and MGH Thoracic Oncology Group as Program Manager in May 2018. Prior to joining MGH, Lia was a Clinical Admin Support Specialist with the GU group at the Dana Farber Cancer Institute. Lia received a Bachelor of Science in Business Administration and a Master of Science in Health and Wellness Management from Merrimack College. Outside the lab Lia enjoys hanging out with family and friends and being active.
Jamie completed his Bachelor and Masters at the University of Sussex, before undertaking his PhD at the University College London. There he worked with Professors Benjamin Chain and Mahdad Noursadeghi, developing methods for high-throughput sequencing and analysis of T cell receptor (TCR) repertoires. He moved from London to MGH to work with Mark Cobbold, exploring immunopeptidomes and TCR repertoires in a range of cancers. Staying within the department, he moved to the Hata lab in September of 2019, where he is working on developing immunotherapies to treat ALK positive lung cancers.
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