Investigating the mechanisms of drug sensitivity and resistance to targeted therapies for lung cancer.

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Featured Publication

Analysis of lorlatinib analogs reveals a roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer.

Published June 20, 2022
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Aaron Hata, MD PhD, Principal Investigator


Our mission is to advance the development of new therapies for patients with lung cancer through scientific discovery of the molecular mechanisms of drug sensitivity and resistance, understanding tumor evolution during treatment, and identification of targetable vulnerabilities to guide investigation of novel therapeutic strategies.

We are a diverse group of physicians & scientists with expertise in cell biology, pharmacology, genetics, immunology and computational biology.

Meet the Team

News — March 17, 2023

Wafa passes PQE

Congratulations to Wafa for passing her Preliminary Qualifying Exam for the Harvard BBS Program today!

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News — March 14, 2023

U Colorado visit

Aaron speaks at the University of Colorado Cancer Center. Thank you to Dr. Sabrina Spencer for hosting. A great opportunity to make new friends and reconnect with former colleagues and…

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We are looking for people to partner with us in our mission to improve treatments for patients with lung cancer.

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We are privileged to partner with a number of individuals and organizations who support our research. We are grateful for their dedication to helping us in the fight against lung cancer.