Lin JJ*, Choudhury NJ*, Yoda S*, Zhu VW, Johnson TW, Sakhtemani R, Dagogo-Jack I, Digumarthy SR, Lee C, Do A, Peterson J, Prutisto-Chang K, Malik W, Hubbeling HG, Langenbucher A, Schoenfeld AJ, Falcon CJ, Temel JS, Sequist LV, Yeap BY, Lennerz JK, Shaw AT, Lawrence MS, Ou SI, Hata AN*, Drilon A*, Gainor JF*. Spectrum of Mechanisms of Resistance to Crizotinib and Lorlatinib in ROS1 Fusion-Positive Lung Cancer. Clin Cancer Res. 2021 Mar 8. doi: 10.1158/1078-0432.CCR-21-0032. Epub ahead of print. PMID: 33685866.
The lab is back open! We have been given the approval to restart our experiments while following strict social distancing and safety measures outlined by the hospital.
Congratulationsto Chendi for receiving a Ruth L. Kirschstein National Research Service Award (NRSA) Postdoctoral Fellowship from the NCI to study targeted therapies for KRAS mutant lung cancer!
Meador CB, Hata AN. Acquired resistance to targeted therapies in NSCLC: Updates and evolving insights. Pharmacol Ther. 2020 Jun;210:107522. doi: 10.1016/j.pharmthera.2020.107522. Epub 2020 Mar 6. PMID: 32151666.
Dagogo-Jack I*, Yoda S*, Lennerz JK, Langenbucher A, Lin JJ, Rooney MM, Prutisto-Chang K, Oh A, Adams NA, Yeap BY, Chin E, Do A, Marble HD, Stevens SE, Digumarthy SR, Saxena A, Nagy RJ, Benes CH, Azzoli CG, Lawrence MS, Gainor JF, Shaw AT*, Hata AN*. MET Alterations Are a Recurring and Actionable Resistance Mechanism in ALK-Positive Lung Cancer. Clin Cancer Res. 2020 Jun 1;26(11):2535-2545. doi: 10.1158/1078-0432.CCR-19-3906. Epub 2020 Feb 21. PMID: 32086345.
Millar DG, Ramjiawan RR, Kawaguchi K, Gupta N, Chen J, Zhang S, Nojiri T, Ho WW, Aoki S, Jung K, Chen I, Shi F, Heather JM, Shigeta K, Morton LT, Sepulveda S, Wan L, Joseph R, Minogue E, Khatri A, Bardia A, Ellisen LW, Corcoran RB, Hata AN, Pai SI, Jain RK, Fukumura D, Duda DG, Cobbold M. Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy. Nat Biotechnol. 2020 Apr;38(4):420-425. doi: 10.1038/s41587-019-0404-8. Epub 2020 Feb 10. PMID: 32042168.
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