Author: Lia Limone
KRAS G12C resistance
Tanaka N*, Lin JJ*, Li C*, Ryan MB, Zhang J, Kiedrowski LA, Michel AG, Syed MU, Fella KA, Sakhi M, Baiev I, Juric D, Gainor JF, Klempner SJ, Lennerz JK, Siravegna G, Bar-Peled L, Hata AN*, Heist RS*, Corcoran RB*. Clinical acquired resistance to KRASG12C inhibition through a novel KRAS switch-II pocket mutation and polyclonal alterations converging on RAS-MAPK reactivation. Cancer Discov. 2021 Apr 6:candisc.0365.2021. doi: 10.1158/2159-8290.CD-21-0365. Online ahead of print. PMID: 33824136
We are now recruiting at all levels! Please see our job postings for a post-doctoral fellow, a research technician to study tumor evolution, a research technician to study tumor microenvironment, and a research technician to study novel T cell therapies for ALK lung cancer, and a research technician for our model development team. For more information, contact us.
Farewell to Aya & Wafa
We say farewell to Aya & Wafa. Aya will be at the University of Tsukuba as a faculty member of medicine and Wafa will be attending Harvard Medical school as a graduate student! Best wishes to you in your future endeavors – we will miss you!
Welcome to Farrah Wakefield who joins our group as a research technician on the model development team.
Our manuscript on APOBEC3A and evolution of drug resistance is now posted on bioRxiv. Congrats to Hideko and the entire team!
Welcome to Adam Acker who joins our group as a research technician on the model development team.
Congratulations to Hideko for receiving a Pilot Grant award from the Lung Cancer Research Foundation to study the role of APOBEC3A in evolution of acquired drug resistance!
Welcome to Marta Herrero Alonso who joins our group as a research technician.