Radhika joined the Hata lab in 2022. She did her Masters in Virology from the National Institute of Virology, India. Radhika received PhD in Cell and Molecular biology from the University of Toledo, Ohio. During her graduate school in Dr. William R. Taylor lab her research focused on the spindle assembly checkpoint and mitotic spindle architecture. In the Hata lab she is working on understanding the role of tumor micro-environment in EGFR mutant lung cancers. Along with mutations in tumor cells, components from tumor micro-environment impact patient response to tyrosine kinase inhibitors. Her goal is to dissect such pathways used by tumor cells for communicating with the surround cells and provide strategies to overcome acquired resistance in lung cancer. In her free time Radhika enjoys hiking, badminton and reading
Katie joined the Hata lab in December 2021 after earning her BS/MS in Biology from Tufts University. At Tufts, she conducted undergraduate research with Julia Gouvea, studying the learning and teaching practices of Biology at multiple grade levels. Dr. Gouvea’s research investigates how model-based reasoning as a biological practice can support deeper learning for students. In the Hata lab, Katie works with Samar on identifying therapeutic strategies for KRAS NSCLS. Outside of the lab, she enjoys riding her bike and teaching others how to ride at the Bicycle Riding School!
We say farewell to Farrah who has moved onto an industry position with Novartis Institutes for Biomedical Research (NIBR) as a Research Scientist for in vivo pharmacology and oncology. Best wishes to you in your future endeavors – we will miss you!
Our manuscript describing Stitchr, a tool for generating full length TCR sequences from minimal V/J/CDR3 information, is now posted on bioRxiv. Congratulations to Jamie and the team!
Hu H, Piotrowska Z, Hare PJ, Chen H, Mulvey HE, Mayfield A, Noeen S, Kattermann K, Greenberg M, Williams A, Riley AK, Wilson JJ, Mao YQ, Huang RP, Banwait MK, Ho J, Crowther GS, Hariri LP, Heist RS, Kodack DP, Pinello L, Shaw AT, Mino-Kenudson M, Hata AN, Sequist LV, Benes CH, Niederst MJ, Engelman JA. Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms. Cancer Cell. 2021 Nov 8;39(11):1531-1547.e10. doi: 10.1016/j.ccell.2021.09.003. Epub 2021 Oct 7. PMID: 34624218
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